Article
Effective models of periodically driven networks.
Biophysical journal - 7 Dec 2011
Shulman Jason, Seemann Lars, Gunaratne Gemunu H
Abstract excerpt
Circadian rhythms are governed by a highly coupled, complex network of genes. Due to feedback within the network, any modification of the system's state requires coherent changes in several nodes. A model of the underlying network is necessary to compute these modifications. We use an effective modeling approach for this task. Rather than inferred biochemical interactions, our method utilizes microarray data from...
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