Article
Extended molecular spectrum of beta- and alpha-thalassemia in Oman.
Hemoglobin - 1 Jan 2010
Hassan Suha M, Hamza Nishat, Jaffer Al-Lawatiya Fatma, Jaffer Mohammed Ali, Harteveld Cornelis L, Rajab Anna, Giordano Piero C
Abstract excerpt
Sickle cell disease is known to be very common in the Omani population, although data are limited concerning beta-thalassemia (beta-thal). We report the molecular background of 87 unrelated patients from the Sultanate of Oman, diagnosed with beta-thal major (beta-TM), beta-thal intermedia (beta-TI) or minor. Diagnosis was based on clinical and hematological data and confirmed by molecular analysis. We found 11...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- Cohort Studies
- Consanguinity
- DNA Mutational Analysis
- Emigrants and Immigrants
- Female
- Gene Deletion
- Gene Frequency
- Humans
- Infant
- Male
- Mutation
- Oman
- Young Adult