Article
Molecular basis of alpha-thalassemia in Algeria.
Hemoglobin - 1 Jan 2008
Mesbah-Amroun Hamida, Rouabhi Fatiha, Ducrocq Rolande, Elion Jacques
Abstract excerpt
An epidemiological molecular study was carried out to evaluate the spectrum and allelic frequency of alpha-thalassemia (alpha-thal) defects in Algeria. A series of 153 randomly selected blood donors was screened for 10 alpha-thal alleles described in the Mediterranean area. In addition, six unrelated cases with hematological and biochemical data suggestive of Hb H disease were investigated. Our data revealed an...
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