Article
Known and new δ-globin gene mutations and other factors influencing Hb A2 measurement in the Omani population.
Hemoglobin - 1 Jan 2014
Hassan Suha M, Harteveld Cornelis L, Bakker Egbert, Giordano Piero C
Abstract excerpt
Although δ-thalassemia (δ-thal) is not categorized as a severe disease, it is essential to know the molecular spectrum of the δ gene mutations frequently occurring in specific areas, particularly if these areas are characterized by a high rate of β-thalassemia (β-thal) such as Oman. This is because coinherited δ-globin gene defects can interfere with the basic diagnosis of a β-thal carrier when this is based upon...
Topics
- Chromatography, High Pressure Liquid
- Codon
- DNA Mutational Analysis
- Female
- Genotype
- Hemoglobin A2
- Humans
- Male
- Mutation
- Oman
- delta-Globins
- delta-Thalassemia