Article
Endoplasmic reticulum chaperone gp96 is essential for infection with vesicular stomatitis virus
29 Mar 2010
Abstract excerpt
The envelope glycoprotein of vesicular stomatitis virus (VSV-G) enables viral entry into hosts as distant as insects and vertebrates. Because of its ability to support infection of most, if not all, human cell types VSV-G is used in viral vectors for gene therapy. However, neither the receptor nor any specific host factor for VSV-G has been identified. Here we demonstrate that infection with VSV and innate...
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