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Article

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation.

Proceedings of the National Academy of Sciences of the United States of America - 27 Apr 2010

Shi Fumin, Telesco Shannon E, Liu Yingting, Radhakrishnan Ravi, Lemmon Mark A

Abstract excerpt

ErbB3/HER3 is one of four members of the human epidermal growth factor receptor (EGFR/HER) or ErbB receptor tyrosine kinase family. ErbB3 binds neuregulins via its extracellular region and signals primarily by heterodimerizing with ErbB2/HER2/Neu. A recently appreciated role for ErbB3 in resistan...

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Identifiers

PMID: 20351256
DOI: 10.1073/pnas.1002753107
PMCID: PMC2867849

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20351256-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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