Article
Treatment with coartem (artemether-lumefantrine) in Papua New Guinea.
The American journal of tropical medicine and hygiene - 1 Apr 2010
Schoepflin Sonja, Lin Enmoore, Kiniboro Benson, DaRe Jeana T, Mehlotra Rajeev K, Zimmerman Peter A, Mueller Ivo, Felger Ingrid
Abstract excerpt
A recent drug efficacy trial reported Coartem (artemether-lumefantrine) to be highly effective against Plasmodium falciparum in children less than 5 years of age in Papua New Guinea (PNG). In contrast, we have observed high levels of treatment failures in non-trial conditions in a longitudinal cohort study in the same age group in PNG. Recrudescences were confirmed by genotyping of three different marker genes to...
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