Article
Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone.
Tropical medicine & international health : TM & IH - 1 Jul 2006
Grandesso Francesco, Hagerman Andres, Kamara Sarian, Lam Eva, Checchi Francesco, Balkan Suna, Scollo Giuseppe, Durand Rémy, Guthmann Jean-Paul
Abstract excerpt
OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous study had shown 70.2% efficacy of amodiaquine in monotherapy. METHODS: Method and outcome classification of the study complied with WHO guidelines. Children 6-59 months with uncomplicated malaria were followed-up for 28 days. PCR...
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