Article
Association of HLA-DQ and HLA-DR alleles with susceptibility or resistance to HIV-1 infection among the population of Chaco Province, Argentina.
Medicina - 1 Jan 2002
Motta Patricia, Marinic Karina, Sorrentino Adrián, López Roxana, Iliovich Ernesto, Habegger de Sorrentino Alicia
Abstract excerpt
The pathogenesis of infections clearly involves immunoregulatory host factors and products of Major Histocompatibility Complex (MHC) genes class II which present antigenic peptides to the T-cell receptor on CD4+ cells which in turn increase the production of specific antibodies and cytotoxic T lymphocytes. The objective of this study was to determine the frequency of the different alleles of HLA class II DQ and...
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