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Regulation of skeletal muscle mitochondrial function: genes to proteins

25 Mar 2010

Abstract excerpt

The impact of ageing on mitochondrial function and the deterministic role of mitochondria on senescence continue to be topics of vigorous debate. Many studies report that skeletal muscle mitochondrial content and function are reduced with ageing and metabolic diseases associated with insulin resistance. However, an accumulating body of literature suggests that physical inactivity typical of ageing may be a more...

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PMID: 20345409
DOI: 10.1111/j.1748-1716.2010.02124.x

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