Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protection by beta-carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: implications for carcinogenesis and anticarcinogenesis.

Free radical biology & medicine - 1 Oct 1992

Rousseau E J, Davison A J, Dunn B

Abstract excerpt

beta-Carotene protects against photooxidative dermatitis in porphyric humans and mice by quenching of photoactivated species. Other actions of beta-carotene in vivo are explained on the basis of its ability to scavenge free radicals in vitro. For example, in guinea pigs treated with CCl4, beta-carotene decreases pentane and ethane production. Epidemiological studies link low serum beta-carotene levels to elevated...

Topics

Animals
Anticarcinogenic Agents
Carotenoids
Free Radical Scavengers
Humans
Mutation
Neoplasms
Reactive Oxygen Species
beta Carotene

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1398219
DOI: 10.1016/0891-5849(92)90183-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1398219-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protection by beta-carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: implications for carcinogenesis and anticarcinogenesis.PMID 1398219Read ↗

Carotenoids and Carcinogenesis: Exploring the Antioxidant and Cell Signaling Roles of Carotenoids in the Prevention of CancerSemantic proximity Read ↗

The Antitumour Mechanisms of Carotenoids: A Comprehensive ReviewSemantic proximity Read ↗

Laboratory and clinical studies of cancer chemoprevention by antioxidants in berriesSemantic proximity Read ↗

Modulation of genotoxic and related effects by carotenoids and vitamin A in experimental models: mechanistic issues.Semantic proximity Read ↗

Carotenoids and Modulation of Cancer: Molecular Targets.Semantic proximity Read ↗

Effects of carotenoids in cellular and animal systemsSemantic proximity Read ↗

Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention.Semantic proximity Read ↗

Carotenoids in Cancer ChemopreventionSemantic proximity Read ↗

Biological activity of lycopene metabolites: implications for cancer preventionSemantic proximity Read ↗

Proanthocyanidins Inhibit Photocarcinogenesis through Enhancement of DNA Repair and Xeroderma Pigmentosum Group A–Dependent MechanismSemantic proximity Read ↗

Overview of Mechanisms of Action of LycopeneSemantic proximity Read ↗

Chlorophylls as anticarcinogens (review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.