Article
Responses of endothelial cells from different vessels to inflammatory cytokines and shear stress: evidence for the pliability of endothelial phenotype.
Journal of vascular research - 1 Jan 2010
Luu N Thin, Rahman Mahbub, Stone Phil C, Rainger G Ed, Nash Gerard B
Abstract excerpt
BACKGROUND/AIMS: Local haemodynamic and stromal microenvironments may determine the phenotype of endothelial cells (EC) and regulate their inflammatory responses. METHODS: We compared neutrophil recruitment by EC from human umbilical veins (HUVEC) or arteries (HUAEC) or from human coronary arteries (HCAEC) after 'static' culture or exposure to shear stress (2 Pa for 24 h) and treatment with tumour necrosis...
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