The genetic impact of the Q551R interleukin-4 receptor alpha polymorphism for aggressive or chronic periodontitis and the occurrence of periodontopathic bacteria.

doi:10.1016/j.archoralbio.2011.06.003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The genetic impact of the Q551R interleukin-4 receptor alpha polymorphism for aggressive or chronic periodontitis and the occurrence of periodontopathic bacteria.

Archives of oral biology - 1 Dec 2011

Reichert Stefan, Stein Jamal M, Klapproth Jana, Zimmermann Uta, Reichert Yvonne, Gläser Christiane, Schaller Hans-Günter, Schulz Susanne

Abstract excerpt

OBJECTIVE: The Q551R polymorphism of the gene encoded for the α chain of the interleukin-4 receptor (IL-4RA) could influence both IL-4 and IL-13 signalling. Since both cytokines could be important in the pathogenesis of periodontitis the aim of this study was to evaluate putative associations of the Q551R polymorphism to generalized aggressive or chronic periodontitis and five periodontopathogens. DESIGN: 154...

Topics

Adult
Aggressive Periodontitis
Alleles
Bacteria
Case-Control Studies
Chi-Square Distribution
Chronic Periodontitis
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Logistic Models

Male

Middle Aged

Mutation

Polymerase Chain Reaction

Polymorphism, Genetic

Receptors, Interleukin-4

Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 21733492
DOI: 10.1016/j.archoralbio.2011.06.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21733492-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic impact of the Q551R interleukin-4 receptor alpha polymorphism for aggressive or chronic periodontitis and the occurrence of periodontopathic bacteria.PMID 21733492Read ↗

Association between IL-4 and IL-4R Polymorphisms and Periodontitis: A Meta-Analysis.Semantic proximity Read ↗

Association analysis of the IL-1 gene cluster polymorphisms with aggressive and chronic periodontitis in the Algerian population.Semantic proximity Read ↗

Polymorphism IL-1RN rs419598 reduces the susceptibility to generalized periodontitis in a population of European descent.Semantic proximity Read ↗

Detection of risk SNPs and periopathogenic bacteria in periodontitis patients and healthy individuals in Slovak populationSemantic proximity Read ↗

Association of OPG, TNF-α, and IL-1B Gene Variants With Periodontitis in a South African Population.Semantic proximity Read ↗

The del/del genotype of the nuclear factor-kappaB -94ATTG polymorphism and its relation to aggressive periodontitis.Semantic proximity Read ↗

Chronic Periodontitis and Immunity, Towards the Implementation of a Personalized Medicine: A Translational Research on Gene Single Nucleotide Polymorphisms (SNPs) Linked to Chronic Oral Dysbiosis in 96 Caucasian PatientsSemantic proximity Read ↗

Interleukin-1β rs1143634 Polymorphism and Susceptibility to Periodontitis in the Iraqi Population.Semantic proximity Read ↗

Polymorphisms of Toll-Like Receptor 4 as a Risk Factor for Periodontitis: Meta-Analysis.Semantic proximity Read ↗

Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis.Semantic proximity Read ↗

Polymorphic Regions in Fc Gamma Receptor and Tumor Necrosis Factor-α Genes and Susceptibility to Chronic Periodontitis in a Cohort From South India.Semantic proximity Read ↗

Association Between Tumor Necrosis Factor-α (G-308A) Polymorphism and Chronic Periodontitis, Aggressive Periodontitis, and Peri-implantitis: A Meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.