Article
Analysis of IL-6, IL-10 and NF-κB Gene Polymorphisms in Aggressive and Chronic Periodontitis.
Central European journal of public health - 1 Jun 2017
Toker Hülya, Görgün Emine Pirim, Korkmaz Ertan Mahir
Abstract excerpt
OBJECTIVE: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-κB(NF-κB). The aim of this study was to ascertain the association between genetic polymorphism of these genes (IL-6(-174), IL-10(-597) and NF-κB1-94ins/del)) and chronic/aggressive periodontitis. METHODS: Forty-five patients with...
Topics
- Adult
- Aggressive Periodontitis
- Alleles
- Case-Control Studies
- Chronic Periodontitis
- Female
- Genotype
- Humans
- Interleukin-10
- Interleukin-6
- Male
- Middle Aged