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Phosphorylation of the virulence regulator SarA modulates its ability to bind DNA in<i>Staphylococcus aureus</i>

19 Feb 2010

Abstract excerpt

Staphylococcus aureus is one of the main bacterial species of clinical importance. Its virulence is considered multifactorial and is attributed to the combined action of a variety of molecular determinants including the virulence regulator SarA. Phosphorylation of SarA was observed to occur in vivo. From this finding, SarA was overproduced and purified to homogeneity. In an in vitro assay, it was found to be...

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PMID: 20337713
DOI: 10.1111/j.1574-6968.2010.01930.x

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