Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.

doi:10.1128/JVI.65.6.3203-3212.1991

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Article

Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.

Journal of virology - 1 Jun 1991

Luban J, Goff S P

Abstract excerpt

We have expressed the human immunodeficiency virus type 1 (HIV-1) gag polyprotein (Pr55gag) in bacteria under the control of the T7 phage gene 10 promoter. When the gene encoding the viral protease is included in cis, in the -1 reading frame, the expected proteolytic cleavage products MA and CA are produced. Disruption of the protease-coding sequence prevents proteolytic processing, and full-length polyprotein is...

Topics

Base Sequence
Binding, Competitive
Collodion
Escherichia coli
Gene Expression
Gene Products, gag
HIV Protease
HIV-1
Hydrogen-Ion Concentration
Hydrolysis
Micropore Filters
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Potassium Chloride

Promoter Regions, Genetic

Protein Precursors

RNA Probes

RNA, Viral

Source

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Identifiers

PMID: 2033671
DOI: 10.1128/JVI.65.6.3203-3212.1991
PMCID: PMC240977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2033671-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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