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Improved taxonomic assignment of human intestinal 16S rRNA sequences by a dedicated reference database

1 Dec 2015

Abstract excerpt

BACKGROUND: Current sequencing technology enables taxonomic profiling of microbial ecosystems at high resolution and depth by using the 16S rRNA gene as a phylogenetic marker. Taxonomic assignation of newly acquired data is based on sequence comparisons with comprehensive reference databases to find consensus taxonomy for representative sequences. Nevertheless, even with well-characterised ecosystems like the...

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PMID: 26651617
DOI: 10.1186/s12864-015-2265-y

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