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Papillomavirus E5: the smallest oncoprotein with many functions

11 Nov 2011

Abstract excerpt

Papillomaviruses (PVs) are established agents of human and animal cancers. They infect cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently associated with cancer of the uterine cervix, but are also involved in the etiopathogenesis of other cancer types. The early oncoproteins of PVs: E5, E6 and E7 are known to contribute to tumour progression. While the oncogenic activities of E6 and...

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PMID: 22078316
DOI: 10.1186/1476-4598-10-140

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