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Planning and Conducting a Pharmacogenetics Association Study.

Clinical pharmacology and therapeutics - 1 Sept 2021

Hertz Daniel L, Arwood Meghan J, Stocco Gabriele, Singh Sonal, Karnes Jason H, Ramsey Laura B

Abstract excerpt

Pharmacogenetics (PGx) association studies are used to discover, replicate, and validate the association between an inherited genotype and a treatment outcome. The objective of this tutorial is to provide trainees and novice PGx researchers with an overview of the major decisions that need to be made when designing and conducting a PGx association study. The first critical decision is to determine whether the...

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PMID: 33880756
DOI: 10.1002/cpt.2270

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