Article
Manganese superoxide dismutase polymorphism, treatment-related toxicity and disease-free survival in SWOG 8897 clinical trial for breast cancer.
Breast cancer research and treatment - 1 Nov 2010
Yao Song, Barlow William E, Albain Kathy S, Choi Ji-Yeob, Zhao Hua, Livingston Robert B, Davis Warren, Rae James M, Yeh I-Tien, Hutchins Laura F, Ravdin Peter M, Martino Silvana, Lyss Alan P, Osborne C Kent, Abeloff Martin D, Hortobagyi Gabriel N, Hayes Daniel F, Ambrosone Christine B
Abstract excerpt
To date, the few studies of associations between a functional polymorphism in the oxidative stress-related gene manganese superoxide dismutase (SOD2) and breast cancer survival have been inconsistent. In a homogeneous patient population from a large cooperative group trial Southwest Oncology Group (SWOG) 8897, we evaluated this polymorphism in relation to both treatment-related toxicity and disease-free survival...
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