Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma.

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Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma.

Molecular vision - 17 Mar 2010

Murakami Kaori, Meguro Akira, Ota Masao, Shiota Tomoko, Nomura Naoko, Kashiwagi Kenji, Mabuchi Fumihiko, Iijima Hiroyuki, Kawase Kazuhide, Yamamoto Tetsuya, Nakamura Makoto, Negi Akira, Sagara Takeshi, Nishida Teruo, Inatani Masaru, Tanihara Hidenobu, Aihara Makoto, Araie Makoto, Fukuchi Takeo, Abe Haruki, Higashide Tomomi, Sugiyama Kazuhisa, Kanamoto Takashi, Kiuchi Yoshiaki, Iwase Aiko, Ohno Shigeaki, Inoko Hidetoshi, Mizuki Nobuhisa

Abstract excerpt

PURPOSE: To investigate whether the GLC1F locus is associated with normal tension glaucoma (NTG) in Japanese patients. METHODS: We recruited 242 unrelated Japanese subjects, including, 141 NTG patients and 101 healthy controls. The patients exhibiting a comparatively early onset were selected as they suggest that genetic factors may show stronger involvement. Genotyping and assessment of allelic diversity was...

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PMID: 20309402
PMCID: PMC2842094

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