Article
Microsatellite analysis of the GLC1B locus on chromosome 2 points to NCK2 as a new candidate gene for normal tension glaucoma.
The British journal of ophthalmology - 1 Sept 2008
Akiyama M, Yatsu K, Ota M, Katsuyama Y, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Kumagai N, Nishida T, Inatani M, Tanihara H, Ohno S, Inoko H, Mizuki N
Abstract excerpt
AIMS: The aim of this study was to investigate the association between normal tension glaucoma and the candidate disease locus glaucoma 1, open angle, B (GLC1B) on chromosome 2. There are many reports describing the results of association or linkage studies for primary open angle glaucoma (POAG), with GLC1B as one of the loci associated with normal or moderately elevated intraocular pressure. However, there are...
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