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Article

Origins of the recent emergence of Plasmodium falciparum pyrimethamine resistance alleles in Madagascar.

Antimicrobial agents and chemotherapy - 1 Jun 2010

Andriantsoanirina Valérie, Bouchier Christiane, Tichit Magali, Jahevitra Martial, Rabearimanana Stéphane, Randrianjafy Rogelin, Ratsimbasoa Arsène, Mercereau-Puijalon Odile, Durand Rémy, Ménard Didier

Abstract excerpt

The combination of sulfadoxine-pyrimethamine is recommended for use as intermittent preventive treatment of malaria during pregnancy and is deployed in Africa. The emergence and the spread of resistant parasites are major threats to such an intervention. We have characterized the Plasmodium falciparum dhfr (pfdhfr) haplotypes and flanking microsatellites in 322 P. falciparum isolates collected from the Comoros...

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Identifiers

PMID: 20308388
DOI: 10.1128/AAC.01511-09
PMCID: PMC2876361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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