Article
Mutation and the evolution of recombination.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Apr 2010
Barton N H
Abstract excerpt
Under the classical view, selection depends more or less directly on mutation: standing genetic variance is maintained by a balance between selection and mutation, and adaptation is fuelled by new favourable mutations. Recombination is favoured if it breaks negative associations among selected alleles, which interfere with adaptation. Such associations may be generated by negative epistasis, or by random drift...
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