The evolution of mutation rates: separating causes from consequences.

doi:10.1002/1521-1878(200012)22:12<1057::AID-BIES3>3.0.CO;2-W

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Article

The evolution of mutation rates: separating causes from consequences.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 2000

Sniegowski P D, Gerrish P J, Johnson T, Shaver A

Abstract excerpt

Natural selection can adjust the rate of mutation in a population by acting on allelic variation affecting processes of DNA replication and repair. Because mutation is the ultimate source of the genetic variation required for adaptation, it can be appealing to suppose that the genomic mutation ra...

Topics

Animals
Biological Evolution
DNA Replication
Genetic Variation
Models, Genetic
Mutation
Selection, Genetic

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