Article
Donor graft does not affect the P450 2C19 genotype expressed in peripheral blood in recipients of living donor liver transplantation.
Clinical transplantation - 1 Jan 2000
Chiu King-Wah, Tai Wei-Chen, Nakano Toshiaki, Tseng Hui-Peng, Cheng Yu-Fan, Jawan Bruno, Goto Shigeru, Chen Chao-Long
Abstract excerpt
The function of cytochrome P450 2C19 (CYP2C19) is altered in patients with end-stage liver disease (ESLD) that require liver transplantation (LT). The status of CYP2C19 is of considerable interest because the transplanted healthy donor livers are perfused with the blood of the recipient with ESLD. This study aims to clarify the changes in CYP2C19 in the peripheral blood before and after LT. Thirty pairs of living...
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