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Article

Gender-dependent penetrance of small heterodimer partner (SHP) gene deficiency in overweight/obese Chinese pedigrees.

The Journal of international medical research - 1 Jan 2000

Yang Z, Wu S, Zheng T, Lu H, Ma X, Jia W, Hu R

Abstract excerpt

Mutations of the small heterodimer partner (SHP) gene have been associated with mild obesity in Japanese subjects. This study was designed to investigate whether there was a similar association in 772 Chinese adults. A total of 272 subjects were normal weight, 423 were overweight and 77 were obese. Four non-synonymous mutations (R34X, H53fsdel10, G171A, G189E) were identified in 10 out of the 500 overweight/obese...

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Identifiers

PMID: 20233523
DOI: 10.1177/147323001003800116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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