Article
Association between genetic variants in the base excision repair pathway and outcomes after hematopoietic cell transplantations.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Aug 2010
Thyagarajan Bharat, Lindgren Bruce, Basu Saonli, Nagaraj Sriharsha, Gross Myron D, Weisdorf Daniel J, Arora Mukta
Abstract excerpt
Alkylating agents with or without ionizing radiation are frequently used in pretransplant conditioning regimens. Damage induced by these agents is commonly repaired by the base excision repair (BER) pathway. Hence, we hypothesized that genetic polymorphisms in the BER pathway will be associated w...
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