Article
[The suppressive effect of HLA-DQw6 genes on collagen-induced arthritis in mice].
Fukuoka igaku zasshi = Hukuoka acta medica - 1 Feb 1991
Kawaharada T
Abstract excerpt
We investigated the effect of HLA-DQw6 genes on collagen-induced arthritis (CIA) in mice, based on our previous observation that the frequency of HLA-DR4-Dw15-DQw4 haplotype was increased in the patients with rheumatoid arthritis (RA) in the Japanese whereas the frequency of HLA-DR2-Dw12-DQw6 was decreased in them significantly. We utilized the HLA-DQw6 genes of transgenic C57BL/6 mice (DQw6-B6) and their F1...
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