Article
Toll-like receptor 4 D299G polymorphism and the incidence of infections in cirrhotic patients.
Alimentary pharmacology & therapeutics - 1 Jun 2010
Guarner-Argente C, Sánchez E, Vidal S, Román E, Concepción M, Poca M, Sánchez D, Juárez C, Soriano G, Guarner C
Abstract excerpt
BACKGROUND: Toll-like receptor (TLR) 4 genetic polymorphisms, mainly D299G, have been associated with increased predisposition to infection in several populations. AIM: To retrospectively analyse the relationship between the presence of the TLR4 D299G polymorphism and the incidence of bacterial infections in cirrhotic patients. METHODS: We included 111 consecutive cirrhotic patients hospitalized with ascites and...
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