Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleotide sequence of canine Smad3.

Biochemical genetics - 1 Apr 2010

Sugiyama Kazutoshi, Ooishi Ryo, Nishino Yoshii, Funaba Masayuki, Murakami Masaru

Abstract excerpt

The whole genome sequence of a Boxer dog suggested that the amino acid sequence of the carboxyl terminus of a putative Smad3 is SSVF-(COOH), not SSVS-(COOH) as in all Smad3 sequences identified in many species. Because phosphorylation of the last two serines at the carboxyl terminus is generally indispensable for Smad3-mediated signaling, the role of Smad3 may be unique in dogs. The present study determines the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Breeding
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Structure, Tertiary

Share to Sequence Analysis, DNA

Share to Smad3 Protein

Share to Species Specificity

Source

Identifiers

PMID: 20221813
DOI: 10.1007/s10528-009-9304-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleotide sequence of canine Smad3.PMID 20221813Read ↗

A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3Semantic proximity Read ↗

Structural determinants of Smad function in TGF-β signaling.Semantic proximity Read ↗

Four types of Smad4 found in the common carp, Cyprinus carpio.Semantic proximity Read ↗

Characterization of variation in the canine suppressor of cytokine signaling-2 (SOCS2) gene.Semantic proximity Read ↗

Smad3 gene C-terminal phosphorylation site mutation aggravates CCl4 -induced inflammation in mice.Semantic proximity Read ↗

Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.Semantic proximity Read ↗

Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.Semantic proximity Read ↗

Identification and characterization of a SSCP marker in the canine signal sequence receptor beta subunit gene.Semantic proximity Read ↗

A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals.Semantic proximity Read ↗

Structural basis of Smad2 recognition by the Smad anchor for receptor activation.Semantic proximity Read ↗

Molecular characterization and genetic variability at κ-casein gene (CSN3) in camels.Semantic proximity Read ↗

Smad2 phosphorylation by type I receptor: contribution of arginine 462 and cysteine 463 In the C terminus of Smad2 for specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.