Article
Integration of gene-expression profiles and pathway analysis in ascending thoracic aortic aneurysms.
Annals of vascular surgery - 1 May 2010
Kim Jae Hyun, Na Chan-Young, Choi Si Young, Kim Hwan Wook, Du Kim Young, Kwon Jong Bum, Chung Mee Young, Hong Jong Myeon, Park Chan Beom
Abstract excerpt
BACKGROUND: Despite the increasing incidence of ascending thoracic aortic aneurysms, their pathogenesis and molecular mechanisms remain unknown. The aim of this study was to identify the biological pathways of genes that are expressed differentially in ascending aortic aneurysms. METHODS: Aneurysm wall tissues were obtained from thoracic aortic aneurysms during their repair and normal thoracic aortas from organ...
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