Article
Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity.
Arthritis and rheumatism - 1 May 2010
Crispín José C, Keenan Brendan T, Finnell Michele D, Bermas Bonnie L, Schur Peter, Massarotti Elena, Karlson Elizabeth W, Fitzgerald Lisa M, Ergin Sukran, Kyttaris Vasileios C, Tsokos George C, Costenbader Karen H
Abstract excerpt
OBJECTIVE: To quantify the expression of CD44 and variant isoforms CD44v3 and CD44v6 on T cells from patients with systemic lupus erythematosus (SLE), and to assess correlations of the level of expression of these molecules with disease manifestations. METHODS: Information on clinical and demographic characteristics was collected, and blood samples were obtained from 72 patients with SLE and 32 healthy control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.