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Article

Activation and genetic modification of human monocyte-derived dendritic cells using attenuated Salmonella typhimurium.

TheScientificWorldJournal - 5 Mar 2010

Michael Agnieszka, John Justin, Meyer Brendan, Pandha Hardev

Abstract excerpt

Live attenuated bacterial vectors, such as Salmonella typhimurium, have shown promise as delivery vehicles for DNA. We have examined two new strains of S. typhimurium and their impact on dendritic cell maturation (CD12-sifA/aroC mutant and WT05-ssaV/aroC, both in TML background). Strain WT05 matured dendritic cells in a more efficient way; caused higher release of cytokines TNF-alpha, IL-12, IL-1beta; and was...

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Source

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Identifiers

PMID: 20209385
DOI: 10.1100/tsw.2010.37
PMCID: PMC5763986

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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