Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability.

Gene - 18 Jul 2005

O'Rourke Thomas W, Doudican Nicole A, Zhang Hong, Eaton Jana S, Doetsch Paul W, Shadel Gerald S

Abstract excerpt

With the exception of base excision repair, conserved pathways and mechanisms that maintain mitochondrial genome stability have remained largely undelineated. In the budding yeast, Saccharomyces cerevisiae, Pif1p is a unique DNA helicase that is localized both to the nucleus and mitochondria, whe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Checkpoint Kinase 2
Share to DNA Helicases
Share to Electron Transport Chain Complex Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Intracellular Signaling Peptides and Proteins

Share to Ribonucleotide Reductases

Share to S Phase

Share to Suppression, Genetic

Source

Identifiers

PMID: 15907372
DOI: 10.1016/j.gene.2005.03.031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15907372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential involvement of the related DNA helicases Pif1p and Rrm3p in mtDNA point mutagenesis and stability.PMID 15907372Read ↗

Loss of mitochondrial DNA under genotoxic stress conditions in the absence of the yeast DNA helicase Pif1p occurs independently of the DNA helicase Rrm3p.Semantic proximity Read ↗

Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins.Semantic proximity Read ↗

Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase.Semantic proximity Read ↗

Pif1 family helicases promote mutation avoidance during DNA replication.Semantic proximity Read ↗

Spontaneous Mutation Rates and Spectra of Respiratory-Deficient Yeast.Semantic proximity Read ↗

The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity.Semantic proximity Read ↗

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity.Semantic proximity Read ↗

Mitochondrial DNA defects in Saccharomyces cerevisiae caused by functional interactions between DNA polymerase gamma mutations associated with disease in human.Semantic proximity Read ↗

mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Telomerase is essential to alleviate pif1-induced replication stress at telomeres.Semantic proximity Read ↗

Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase.Semantic proximity Read ↗

Transcription-dependent DNA transactions in the mitochondrial genome of a yeast hypersuppressive petite mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.