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Article

CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19.

European journal of immunology - 1 May 2010

Britschgi Mirjam R, Favre Stéphanie, Luther Sanjiv A

Abstract excerpt

Mice deficient in CCR7 signals show severe defects in lymphoid tissue architecture and immune response. These defects are due to impaired attraction of CCR7+ DC and CCR7+ T cells into the T zones of secondary lymphoid organs and altered DC maturation. It is currently unclear which CCR7 ligand med...

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Source

Identifiers

PMID: 20201039
DOI: 10.1002/eji.200939921

Genes

CCL19
CCL21
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20201039-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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