Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

To Seek Shelter from the Wnt in Osteoarthritis? Wnt-Signaling as a Target for Osteoarthritis Therapy

24 Mar 2010

Abstract excerpt

Recent evidence from animal experiments and clinical samples points at a role for Wnt-signaling in osteoarthritis (OA) pathology. These pathways are key inducers and regulators of joint development, and are involved in formation of bone, cartilage and also synovium. Disregulation of members from this pathways have been described in OA. This makes the Wnt-family of proteins and signaling pathways an attractive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Osteoarthritis Treatment and Mechanisms
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20199388
DOI: 10.2174/138945010791011901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

To Seek Shelter from the Wnt in Osteoarthritis? Wnt-Signaling as a Target for Osteoarthritis TherapyPMID 20199388Read ↗

Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis.Semantic proximity Read ↗

Picking a bone with WISP1 (CCN4): new strategies against degenerative joint diseaseSemantic proximity Read ↗

The involvement of signaling pathways in the pathogenesis of osteoarthritis: An updateSemantic proximity Read ↗

Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease developmentSemantic proximity Read ↗

WNT signaling and cartilage: of mice and men.Semantic proximity Read ↗

The Interaction between microRNAs and the Wnt/β-Catenin Signaling Pathway in OsteoarthritisSemantic proximity Read ↗

BMP signaling: A significant player and therapeutic target for osteoarthritisSemantic proximity Read ↗

MicroRNA-1 Modulates Chondrocyte Phenotype by Regulating FZD7 of Wnt/ β-Catenin Signaling Pathway.Semantic proximity Read ↗

Endochondral Ossification Signals in Cartilage Degradation During Osteoarthritis Progression in Experimental Mouse ModelsSemantic proximity Read ↗

Perspectives on Wnt Signal Pathway in the Pathogenesis and Therapeutics of Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Brief Report: Induction of Matrix Metalloproteinase Expression by Synovial Wnt Signaling and Association With Disease Progression in Early Symptomatic OsteoarthritisSemantic proximity Read ↗

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt‐16 expression and signaling after injury and in osteoarthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.