Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-1 Modulates Chondrocyte Phenotype by Regulating FZD7 of Wnt/ β-Catenin Signaling Pathway.

Cartilage - 1 Dec 2021

Yang Yang, Wang Yawei, Jia Haobo, Li Bing, Xing Dan, Li Jiao Jiao

Abstract excerpt

OBJECTIVE: Osteoarthritis (OA) is an incurable joint disease characterized by pronounced pain. MicroRNAs constitute epigenetic mechanisms that may affect OA progression by contributing to changes in chondrocyte phenotype. This study investigates for the first time whether there is a link between miRNA-1 (miR-1) and OA pathogenesis, and the molecular mechanisms involved. DESIGN: OA-associated gene expression,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Cells, Cultured
Share to Chondrocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Phenotype

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 33215510
DOI: 10.1177/1947603520973255
PMCID: PMC8804847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-1 Modulates Chondrocyte Phenotype by Regulating FZD7 of Wnt/ β-Catenin Signaling Pathway.PMID 33215510Read ↗

The Interaction between microRNAs and the Wnt/β-Catenin Signaling Pathway in OsteoarthritisSemantic proximity Read ↗

Inhibition of miR-199b-5p reduces pathological alterations in Osteoarthritis by potentially targeting <i>Fzd6</i> and <i>Gcnt2</i>Semantic proximity Read ↗

The complex landscape of microRNAs in articular cartilage: biology, pathology, and therapeutic targetsSemantic proximity Read ↗

Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytesSemantic proximity Read ↗

MicroRNA in osteoarthritis: physiopathology, diagnosis and therapeutic challengeSemantic proximity Read ↗

MicroRNAs’ Involvement in Osteoarthritis and the Prospects for TreatmentsSemantic proximity Read ↗

MicroRNAs play a role in chondrogenesis and osteoarthritis (Review)Semantic proximity Read ↗

The Role of MicroRNAs in the Pathophysiology of OsteoarthritisSemantic proximity Read ↗

IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritisSemantic proximity Read ↗

Identification of miR-338-5p and miR-4776-3p as mediators of articular cartilage degenerationSemantic proximity Read ↗

MiR-144-3p Inhibits BMSC Proliferation and Osteogenic Differentiation Via Targeting FZD4 in Steroid-Associated OsteonecrosisSemantic proximity Read ↗

Role of MicroRNA in OsteoarthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.