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Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes

2 Mar 2010

Abstract excerpt

AIMS/HYPOTHESIS: MicroRNAs regulate a broad range of biological mechanisms. To investigate the relationship between microRNA expression and type 2 diabetes, we compared global microRNA expression in insulin target tissues from three inbred rat strains that differ in diabetes susceptibility. METHODS: Using microarrays, we measured the expression of 283 microRNAs in adipose, liver and muscle tissue from...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 20198361
DOI: 10.1007/s00125-010-1667-2

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