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Article

An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jun 2010

Veselska Renata, Skoda Jan, Loja Tomas, Zitterbart Karel, Pavelka Zdenek, Smardova Jana, Valaskova Iveta, Hermanova Marketa, Sterba Jaroslav

Abstract excerpt

PURPOSE: The aim of this study was to perform a detailed cytogenetic and molecular genetic analysis of a tumor taken from a 14.5-year-old boy with glioblastoma multiforme who showed an atypical clinical course. METHODS: Formalin-fixed, paraffin embedded tumor tissue and the corresponding HGG-02 c...

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Source

Identifiers

PMID: 20195615
DOI: 10.1007/s00381-010-1110-5

Genes

EGFR
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20195615-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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