Article
Decoupling Environment-Dependent and Independent Genetic Robustness across Bacterial Species.
PLoS computational biology - 26 Feb 2010
Freilich Shiri, Kreimer Anat, Borenstein Elhanan, Gophna Uri, Sharan Roded, Ruppin Eytan
Abstract excerpt
The evolutionary origins of genetic robustness are still under debate: it may arise as a consequence of requirements imposed by varying environmental conditions, due to intrinsic factors such as metabolic requirements, or directly due to an adaptive selection in favor of genes that allow a species to endure genetic perturbations. Stratifying the individual effects of each origin requires one to study the...
Topics
- Bacteria
- Bacterial Physiological Phenomena
- Computational Biology
- Computer Simulation
- Environment
- Genetic Variation
- Metabolic Networks and Pathways
- Models, Genetic
- Selection, Genetic
- Systems Biology