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Article

Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation.

Cancer genetics and cytogenetics - 1 Mar 2010

Soucek Karel, Gajdusková Pavla, Brázdová Marie, Hýzd'alová Martina, Kocí Lenka, Vydra David, Trojanec Radek, Pernicová Zuzana, Lentvorská Lenka, Hajdúch Marián, Hofmanová Jirina, Kozubík Alois

Abstract excerpt

Stable cell lines obtained by spontaneous immortalization might represent early stages of malignant transformation and be useful experimental models for studies of mechanisms of cancer development. The FHC (fetal human cells) cell line has been established from normal fetal colonic mucosa. Detailed characterization of this cell line and mechanism of spontaneously acquired immortality have not been described yet....

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PMID: 20193843
DOI: 10.1016/j.cancergencyto.2009.11.009

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MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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