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Article

Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke.

Clinica chimica acta; international journal of clinical chemistry - 3 Jun 2010

Shyu Hann-Yeh, Fong Chin-Shih, Fu Yi-Ping, Shieh Jia-Ching, Yin Jiu-Haw, Chang Ching-Yi, Wang Hsiao-Wei, Cheng Chun-Wen

Abstract excerpt

BACKGROUND: Gamma-glutamyl carboxylation, a reaction essential for the biosynthesis of vitamin K-dependent coagulation factors, requires the participation of the gamma-glutamyl carboxylase (GGCX), vitamin K epoxide reductase (VKORC1), and NAD(P)H:quinone oxidoreductase (NQO1). We evaluated the ro...

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Source

Identifiers

PMID: 20193673
DOI: 10.1016/j.cca.2010.02.071

Genes

NQO1
VKORC1
GGCX

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20193673-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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