Article
Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1.
Oncogene - 13 May 2010
Cobbold L C, Wilson L A, Sawicka K, King H A, Kondrashov A V, Spriggs K A, Bushell M, Willis A E
Abstract excerpt
The 5' untranslated region of the proto-oncogene c-myc contains an internal ribosome entry segment (IRES) and c-myc translation can therefore be initiated by internal ribosome entry as well as by cap-dependent mechanisms. It has been shown previously that in patients with multiple myeloma (MM) an...
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