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Article

Study on collateral sensitivity of tigecycline to colistin-resistant Enterobacter cloacae complex.

Microbiology spectrum - 1 Jul 2025

Yu Kaixin, Wu Jiming, Liao Mingjing, Wang Jianmin, Wei Chunli, Long Wenzhang, Gou Xuemei, Yang Yang, Wang Jin, Liang Xushan, Li Chunjiang, Zhang Xiaoli

Abstract excerpt

The past decade has witnessed the emergence and spread of carbapenem-resistant Enterobacter cloacae complex (CRECC), presenting a significant clinical challenge and urgently demanding new treatment strategies against antimicrobial resistance (AMR). This study focused on the impact of tigecycline on the susceptibility of CRECC isolates to colistin and the collateral sensitivity in CRECC. Under tigecycline...

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Identifiers

PMID: 40407373
DOI: 10.1128/spectrum.03310-24
PMCID: PMC12210861

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