Article
Analysis of the functions of glycoproteins E and I and their promoters during VZV replication in vitro and in skin and T-cell xenografts in the SCID mouse model of VZV pathogenesis.
Current topics in microbiology and immunology - 1 Jan 2010
Arvin Ann M, Oliver Stefan, Reichelt Mike, Moffat Jennifer F, Sommer Marvin, Zerboni Leigh, Berarducci Barbara
Abstract excerpt
The two VZV glycoproteins, gE and gI, are encoded by genes that are designated open reading frames, ORF67 and ORF68, located in the short unique region of the VZV genome. These proteins have homologs in the other alphaherpesviruses. Like their homologues, VZV gE and gI exhibit prominent co-locali...
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