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Article

Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Mihaescu Raluca, Detmar Symone B, Cornel Martina C, van der Flier Wiesje M, Heutink Peter, Hol Elly M, Rikkert Marcel G M Olde, van Duijn Cornelia M, Janssens A Cecile J W

Abstract excerpt

Alzheimer's disease (AD) is the most prevalent form of dementia and the number of cases is expected to increase exponentially worldwide. Three highly penetrant genes (AbetaPP, PSEN1, and PSEN2) explain only a small number of AD cases with a Mendelian transmission pattern. Many genes have been ana...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20182048
DOI: 10.3233/JAD-2010-1410

Genes

APOE
PSEN1
PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20182048-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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