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Article

Two different forms of palindrome resolution in the human genome: deletion or translocation.

Human molecular genetics - 15 Apr 2008

Kato Takema, Inagaki Hidehito, Kogo Hiroshi, Ohye Tamae, Yamada Kouji, Emanuel Beverly S, Kurahashi Hiroki

Abstract excerpt

Regions containing palindromic sequence are known to be susceptible to genomic rearrangement in prokaryotes and eukaryotes. Palindromic AT-rich repeats (PATRR) are hypervariable in the human genome, manifesting size polymorphisms and a propensity to rearrange. Size variations are mainly the result of internal deletions, while two PATRRs on 11q23 and 22q11 (PATRR11 and 22) contribute to generation of the t(11;22),...

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Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Genomic Instability

Share to Mutagenesis, Insertional

Share to Nucleic Acid Conformation

Share to Repetitive Sequences, Nucleic Acid

Share to Translocation, Genetic

Source

Identifiers

PMID: 18184694
DOI: 10.1093/hmg/ddn008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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