Article
Genetic variation affects de novo translocation frequency.
Science (New York, N.Y.) - 17 Feb 2006
Kato Takema, Inagaki Hidehito, Yamada Kouji, Kogo Hiroshi, Ohye Tamae, Kowa Hiroe, Nagaoka Kayuri, Taniguchi Mariko, Emanuel Beverly S, Kurahashi Hiroki
Abstract excerpt
Translocation is one of the most frequently occurring human chromosomal aberrations. The constitutional t(11;22)(q23;q11), which is the only known recurrent non-Robertsonian translocation, represents a good model for studying translocations in humans. Here we demonstrate polymorphisms of the pali...
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