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Article

Suppression of Melanin Production by Expression of HSP70

23 Feb 2010

Abstract excerpt

Skin hyperpigmentation disorders due to abnormal melanin production induced by ultraviolet (UV) irradiation are both a clinical and cosmetic problem. UV irradiation stimulates melanin production in melanocytes by increasing intracellular cAMP. Expression of heat shock proteins (HSPs), especially HSP70, is induced by various stressors, including UV irradiation, to provide cellular resistance to such stressors. In...

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PMID: 20177067
DOI: 10.1074/jbc.m110.103051

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Suppression of Melanin Production by Expression of HSP70PMID 20177067Read ↗

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Heat Shock Transcription Factor-1 Regulates Heat Shock Protein-72 Expression in Human Keratinocytes Exposed to Ultraviolet B LightSemantic proximity Read ↗

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